The current issue of Neuron contains a scientific debate that bears watching. It is about one of the great mysteries of amyloid-β precursor protein (APP), that is, its physiological role. Scientists ...

The carving up of the amyloid precursor protein (APP) by the successive action of β- and γ-secretases liberates Aβ, but also yields a small intracellular fragment, the APP intracellular domain (AICD).

Activation-induced cell death (AICD) of immune cells is widely believed to be crucial for the regulation of immune responses. Although macrophage apoptosis has been observed under a variety of ...

If you haven’t had to perform CPR for a patient who was being shocked by an automated implant­able cardioverter defibrillator (AICD), give it time. Approximately 800,000 people in the United States ...