Over the last decade, poisonings and deaths linked to the use of local anesthetics have decreased. Even so, poisonings from one commonly used anesthetic, lidocaine, have increased in the United States ...

A new study published in the Feb. 2012 issue of Anesthesiology found that the type of lipid emulsion used to reverse toxicity of local anesthetics may change the effectiveness of the reversal, ...

Site 1 sodium channel blockers such as tetrodotoxin and saxitoxin are small-molecule drugs with powerful local anesthetic properties. They provide pain relief without toxic effects on local nerves and ...

The American Society of Regional Anesthesia and Pain Medicine has published a practice advisory on local anesthetic systemic toxicity (LAST) called “Guidelines for the Management of Severe Local ...

A liposomal formulation of a local anesthetic shows promise for long-lasting pain relief with minimal toxicity, reports a research group led by Daniel S. Kohane of Harvard Medical School (Proc. Natl.

Lipid emulsion therapy has emerged over the past two decades as a life-saving intervention for local anaesthetic systemic toxicity (LAST). Intravenous administration of a triglyceride-rich emulsion ...

Please provide your email address to receive an email when new articles are posted on . Use of tumescent anesthesia allows for equal anesthetic distribution across large areas while decreasing the ...

Site 1 sodium channel blockers such as tetrodotoxin and saxitoxin are small-molecule drugs with powerful local anesthetic properties. They provide pain relief without toxic effects on local nerves and ...

The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

All current local anesthetics block sensory signals—pain—but they also interrupt motor signals, which can be problematic. For example, too much epidural anesthesia can prevent mothers in labor from ...