DNA is the raw material of modern medicine yet is the only part of drug development not accessible at the lab bench. DNA synthesis, the first step in most biological workflows including gene synthesis ...

DNA synthesis is vital to several processes in biopharmaceutical innovation, including the development of gene therapies, CRISPR gene editing, antisense oligonucleotides and RNA therapies. The need ...

From synthetic biology and gene therapy to data storage and biofuel production, the demand for synthetic DNA is rising. (1) Chemicals remove the 5’-hydroxyl protecting group. The nucleosides are rich ...

Translesion DNA synthesis (TLS) is a specialised branch of the DNA damage tolerance pathway that enables eukaryotic cells to replicate past lesions that would otherwise stall the replication machinery ...

- The next frontier in oligonucleotide synthesis is the direct synthesis of gene-length sequences. - Ansa synthesized a 1005 base long oligonucleotide with industry-leading accuracy. - Ansa will be ...

Genetic medicines such as cell and gene therapies and mRNA vaccines offer extraordinary promise for treating a variety of diseases, including genetic disorders, cancer, and autoimmune diseases. These ...

Scientists have just discovered an entirely new way that DNA can be synthesized. The business of constructing DNA (deoxyribonucleic acid, to give it its full name) usually requires a template that ...

A team of researchers at IOCB Prague led by Prof. Michal Hocek has developed a novel method for preparing ribonucleic acid (RNA) containing modified bases. Innovative use of engineered DNA polymerases ...

It’s a bit like giving the soil a DNA test.” A new droplet digital PCR (ddPCR) method quantifies root DNA directly from soil ...