Patients in UKALL XI were simultaneously recruited by the UK Childhood Cancer Study, 20 an independent case–control epidemiological study designed to assess the impact of environmental carcinogen ...

The main aim of this study was to evaluate the significance of HLA-DPB1 expression in acute graft-versus-host disease (GVHD) after hematopoietic cell transplantation ...

Allogeneic blood and marrow transplantation (allo-BMT) from volunteer unrelated donors can cure patients with malignant and nonmalignant hematologic diseases who lack a suitable family member donor.

Determining the specificity of HLA antibodies is arguably one of the most important contributions by the HLA laboratory today. For patients that have low-to-moderate levels of antibody, using a ...

reacts with the β-chain of the α β heterodimer of all products of the gene families DP, DQ and DR; does not react with erythrocytes and megakaryocytes ...

Here’s a scenario: you’ve recently been diagnosed with leukemia and find yourself needing a blood stem cell transplant (or, in scientific parlance, a hematopoietic stem cell transplant, HSCT) as part ...

Tasked with presenting thousands of unique antigens to T cells, the proteins that form the major histocompatibility complex arise from genes on the human leukocyte antigen (HLA) locus—the most ...