The US Food and Drug Administration (FDA) has issued draft guidance on the development of local anesthetic products with a prolonged duration of effect that can last for days. The guidance, published ...

Nanoparticle-based systems for local anaesthesia harness submicrometre carriers to deliver anaesthetic agents directly to peripheral nerves or tissue sites, thereby prolonging analgesic effect while ...

All current local anesthetics block sensory signals—pain—but they also interrupt motor signals, which can be problematic. For example, too much epidural anesthesia can prevent mothers in labor from ...

CAMBRIDGE, MA -- When patients undergo general anesthesia, doctors can choose among several drugs. Although each of these drugs acts on neurons in different ways, they all lead to the same result: a ...

A new study finds that an easily measurable brain wave shift of phase may be a universal marker of unconsciousness under general anesthesia. At the level of molecules and cells, ketamine and ...

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Discovering a common mechanism used by three anesthesia drugs could lead to a universal anesthesia-delivery system to monitor patients more effectively. When patients undergo general anesthesia, ...

When patients undergo general anesthesia, doctors can choose among several drugs. Although each of these drugs acts on neurons in different ways, they all lead to the same result: a disruption of the ...

Operating rooms and ASCs are facing persistent shortages of anesthetic agents, forcing anesthesia teams to substitute drugs and alter workflows. As of June 19, the FDA listed 194 drugs in shortage, ...

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Researchers have recorded direct evidence that the human hippocampus continues to process spoken words, grammar, and meaning ...