Glucarpidase should soon be approved throughout Europe to treat methotrexate toxicity. The European Medicine Agency's Committee for Medicinal Products for Human Use (CHMP) recently recommended the ...
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Folinic acid and folate: What’s the difference and which is better?
Medically reviewed by Allison Herries, RDN Key Takeaways Folinic acid is an active form of folate, while folic acid must be ...
Patients with methotrexate-associated acute kidney injury (AKI) had better odds of kidney recovery when treated with glucarpidase (Voraxaze), researchers found. Treatment with glucarpidase was ...
A major new study has found a method to identify people who may experience blood, kidney, or liver related side effects from methotrexate, the most commonly used immune-suppressing medicine with 1.3 ...
An FDA-approved medication called glucarpidase could serve as an antidote to kidney toxicity in patients receiving the chemotherapy drug methotrexate (MTX), according to a new study by investigators ...
Methotrexate is a cornerstone in oncology and immunosuppression, but its propensity to disrupt spermatogenesis, deplete antioxidants and trigger apoptosis within the testicular microenvironment ...
A prospective trial of prophylaxis and treatment (P+T) of acute tumor lysis syndrome (ATLS) with rasburicase (R) and nonalkaline hydration in children and adolescents (C+A) with intermediate- (Group B ...
An FDA-approved medication called glucarpidase could serve as an antidote to kidney toxicity in patients receiving the chemotherapy drug methotrexate (MTX), according to a new study. Using data from ...
Please provide your email address to receive an email when new articles are posted on . Patients who received glucarpidase for acute kidney injury from methotrexate treatment had improved kidney ...
Prednisone is recommended as the first-line treatment for pulmonary sarcoidosis, but this steroid causes a number of unwanted side effects. Now new research published at the ATS 2025 International ...
Rheumatoid arthritis (RA) is a chronic condition that occurs when the immune system attacks healthy joints. Doctors may treat the resulting inflammation and pain with methotrexate, a drug that ...
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