Skeletal muscle organoids help scientists bypass bottlenecks in satellite cell production for muscle regeneration research. Researchers typically create organoid models for other biological systems ...

Scientists at UCLA discovered a surprising reason aging muscles heal more slowly. In older muscle stem cells, a protein called NDRG1 builds up and acts like a brake, slowing the cells’ ability to jump ...

Losing muscle strength is a natural part of aging. At the core of this decline is a drop in the number of muscle stem cells (MuSCs), the specialized cells responsible for maintaining and regenerating ...

A new study generated one of the most comprehensive spatially resolved transcriptomic maps of cellular communication between ...

Muscle tissue from aged mice seven days after injury. Left: Aged mice with normal NDRG1 levels show slower regeneration with smaller muscle fibers. Right: Aged mice in which NDRG1 was recently blocked ...

As individuals age, the muscles used to walk up stairs and carry groceries gradually weaken, making everyday tasks more difficult. That same decline can happen because of illnesses like muscular ...

When bones break and there is extreme tissue loss--such as after a car accident or a battlefield injury--current treatments don't often lead to effective healing. But certain stem cells from skeletal ...

Our biceps and our brain cells may have more in common than previously thought. New research led by the Lippincott-Schwartz Lab shows that a network of subcellular structures similar to those ...

Before testing new therapies in animals, researchers now have a more efficient starting point—lab-grown canine muscle cells that can help identify what works and what doesn't. Developed at the Texas A ...