I read the GOULASH trial with great interest. This multicentre, double-blind randomised clinical trial compared early high-energy enteral nutrition (30 kcal/kg/day) with a gradually increasing energy ...

3 The Charles Bronfman Institute for Personalized Medicine, Genetics of Obesity & Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, USA 4 Institute for Community ...

Background and aim Disease activity for Crohn's disease (CD) and UC is typically defined based on symptoms at a moment in time, and ignores the long-term burden of disease. The aims of this study were ...

Correspondence to Dr Richard C Pollok, Gastroenterology, St George's University Hospitals NHS Foundation Trust, London SW17 0QT, UK; richard.pollok{at}nhs.net Objective Depression is a potential risk ...

1 Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Third Military ...

1 National Centre for Bowel Research and Surgical Innovation and GI Physiology Unit, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK Objective The ...

Background: Patients with irritable bowel syndrome (IBS) often feel they have some form of dietary intolerance and frequently try exclusion diets. Tests attempting to predict food sensitivity in IBS ...

Background Clinicians use fibrosis in a liver biopsy to predict clinical outcomes of chronic liver disease. The performance of non-invasive tests has been evaluated against histological assessment of ...

Correspondence to Dr Guangfu Jin, Department of Epidemiology and Biostatistics School of Public Health, Nanjing Medical University, Nanjing, 211166, China; guangfujin{at}njmu.edu.cn ...

Objective Microscopic colitis (MC) is a common cause of chronic diarrhoea, often with additional symptoms. No validated instruments exist to assess disease activity in MC, making it difficult to ...

Background/Aim Hepatic encephalopathy (HE) is common among patients with liver cirrhosis with 30–40% of patients decompensating with overt HE during their clinical course. 1 The American Association ...

The main purposes of research in cholangiocarcinoma (CCA) are prevention, early diagnosis and the development of effective therapies tailored to each patient’s clinical course and general condition.1 ...