Abstract:. For people with localized, high-risk prostate cancer, treatment with 6 months of apalutamide and androgen deprivation therapy (ADT) both before and after surgery reduces the risk of ...
Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...
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Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...
Copyright held by the owner/author(s).
13Huntsman Cancer Institute, Salt Lake City, UT.
Cancer Res (2026) 86 (8_Supplement): LB407.
AbstractIntroduction:. Conversion of androgens to estrogens within breast tumors by aromatization plays a pivotal role in the proliferation of tumor cells expressing the estrogen receptor (ER).
Abstract. High-throughput screening (HTS) of cereblon (CRBN) molecular glue (MG)-biased libraries remains a key strategy for proof-of-concept studies and hit identification against emerging targets.
Melanoma incidence, metastasis, and mortality are significantly associated with age. Interestingly within the clinic, melanoma incidence is low in young adults, peaks between ages 65-79, and decreases ...
Abstract. Antibody-drug conjugates (ADCs) enable the specific targeting of a potent cytotoxic drug to cancer cells expressing a select antigen via the release of the cytotoxin covalently linked to a ...
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