Ligand-dependent enhancer activation indirectly modulates non-target promoters in a chromatin domain
Ligand-driven enhancer activation selectively boosts target gene expression while indirectly repressing neighboring non-target genes, revealing dynamic and competitive regulation during early ...
Researchers have developed a new tool that can screen genes involved in human development at unprecedented scale and speed, using it in a proof-of-principle study to reveal new insights into human ...
A study suggests babies’ brains recognize music from as young as three months of age, while spontaneous movements to music emerge by their first birthday and their ability to match movements to it ...
Genes associated with male reproductive biology appear to be under relaxed selective constraint in a primate species with low sperm competition.
Although auditory encoding of music is robust early in infancy, the transformation of this input into movement patterns develops substantially over the first postnatal year, without reaching full ...
Analysis of data across many different studies shows that children's word recognition improves continuously from infancy through age 5 years, and shows strong coupling with early vocabulary.
Findings suggest placental mammals that lived in China following the most recent mass extinction evolved large teeth before developing more specialized dental structures associated with different ...
Specialized anatomical structures in the mouth and feet of tsetse flies help them feed on blood from a variety of hosts.
Metabolic dysfunction-associated steatotic liver disease (MASLD) progression involves the replacement of protective embryo-derived Kupffer cells (KCs) by inflammatory monocyte-derived macrophages ...
Keratinocytes, which activate an EMT-like program in the skin, can prevent melanoma invasion, highlighting how changes in the tumor microenvironment can act as restraining forces in cancer.
Dissecting protective versus detrimental immune responses uncovers biomarkers and mechanisms that can inform the rational design and evaluation of live attenuated vaccines against African swine fever ...
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